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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | EVALUATION OF ANTI-OXIDANT AND ANTI-UROLITHIATIC ACTIVITY OF NATHAI CHOORI SEEDS BY ETHYLENE GLYCOL AND AMMONIUM CHLORIDE INDUCED UROLITHIASIS IN WISTAR RATS |
| Authors Name: | Mohankumar R , Dr.M.Sakthi Abirami |
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IJNRD_200750
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| Published Paper Id: | IJNRD2308365 |
| Published In: | Volume 8 Issue 8, August-2023 |
| DOI: | |
| Abstract: | Kidney stones, also known as urolithiasis, are characterised by the presence of dense mineral deposits in the urinary tract. This study used an albino Wistar rat model of urolithiasis induced by ethylene glycol and ammonium chloride to assess the anti-urolithiatic efficacy of Methanolic extract of Spermacoce neohispida Goaverts (Me.Sh) seeds. The rats were split into five groups and given various treatments for a total of 28 days. In comparison to the disease control group, the results demonstrated a considerable improvement in the treatment and standard groups. Creatinine, uric acid, urea, and calcium levels were lower in the treatment group than in the control group, according to serum analysis. Magnesium levels increased, whereas calcium and oxalate levels in the urine were markedly decreased. Positive changes were also seen in urine volume, urine pH. Histopathological examination of kidney sections confirmed that the treatment and standard groups displaying normal renal architecture. According to these findings, Me.Sh shows remarkable anti-urolithiatic potential and may be utilised to prevent and treat urinary stone formation. Further research is necessary to determine whether Nathai choori's therapeutic benefits can be used to treat urolithiasis. |
| Keywords: | Urolithiasis, Spermacoce neohispida Goaverts, Borreria hispida, Nathai choori. |
| Cite Article: | "EVALUATION OF ANTI-OXIDANT AND ANTI-UROLITHIATIC ACTIVITY OF NATHAI CHOORI SEEDS BY ETHYLENE GLYCOL AND AMMONIUM CHLORIDE INDUCED UROLITHIASIS IN WISTAR RATS", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 8, page no.d445-d454, August-2023, Available :http://www.ijnrd.org/papers/IJNRD2308365.pdf |
| Downloads: | 000118765 |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2308365 Registration ID: 200750 Published In: Volume 8 Issue 8, August-2023 DOI (Digital Object Identifier): Page No: d445-d454 Country: chennai, TAMIL NADU, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2308365 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2308365 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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