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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | An observational study to determine causation, clinical profile and prognosis of pancytopenia in a tertiary care center |
| Authors Name: | Akhil karun , Madhusudhan C , Teenachandran |
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IJNRD_206526
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| Published Paper Id: | IJNRD2310079 |
| Published In: | Volume 8 Issue 10, October-2023 |
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| Abstract: | Objective :To see the clinical profile, etiological factors and laboratory parameters in patients with pancytopenia. Design :Prospective observational study Setting :A large, academic, tertiary medical center Methodology: Clinical and laboratory data of all patients with a primary diagnosis of pancytopenia was taken . The various etiological factors, clinical presentations and lab investigations were taken into account and compared and prognosis was assessed for each patient Results: A male preponderance was observed, and the majority of patients were aged below 60 years. The most common clinical features were pallor and splenomegaly. 67 percent of patients had hemoglobin less than 7 g%; whereas around 50% of the sample had WBC < 2000 and platelets less than 50000, 52 % had vitamin B12 deficiency, 32% had folic acid deficiency and 19% had a deficiency of both. The most common cause of pancytopenia was Vit B12 deficiency ( 52%) , followed by leukemias and plasma cell dyscrasias ( 19%) and aplastic anemia ( 13%) Interpretation and conclusion: Several easily recognisable and treatable conditions can manifest as pancytopenia. Prompt management of such conditions, notably sepsis and megaloblastic anaemia, can result in the resolution of the cytopenias and negate the need for a BME. Pancytopenia investigations, when guided by appropriate clinic-laboratory findings, can promptly identify the underlying aetiology, while also identifying cases where an expedited BME is required. Key words: Aplastic anemia, Bone marrow biopsy, Megaloblastic anemia, Pancytopenia Corresponding authors :Dr Akhil Karun*,Dr Madhusudhan C**,Dr Teena chandran*** *Post graduate, SIMS&RC, Bangalore **Associate Professor ,SIMS&RC, Bangalore ***Senior Resident, SIMS&RC, Bangalore |
| Keywords: | Aplastic anemia, Bone marrow biopsy, Megaloblastic anemia, Pancytopenia |
| Cite Article: | "An observational study to determine causation, clinical profile and prognosis of pancytopenia in a tertiary care center", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 10, page no.a701-a706, October-2023, Available :http://www.ijnrd.org/papers/IJNRD2310079.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2310079 Registration ID: 206526 Published In: Volume 8 Issue 10, October-2023 DOI (Digital Object Identifier): Page No: a701-a706 Country: Bangalore, karnataka, India Research Area: Health Science Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2310079 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2310079 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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