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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | An observational study to determine clinical profile,immunological profile of MCTD patients and adverse events developed during the duration of treatment. |
| Authors Name: | Nandeesh H U , Teena chandran , Amrutha M K |
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IJNRD_206825
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| Published Paper Id: | IJNRD2310141 |
| Published In: | Volume 8 Issue 10, October-2023 |
| DOI: | |
| Abstract: | Abstract : Background: Mixed connective tissue disease (MCTD) is a rare autoimmune disease, characterized by the production of specific autoantibody anti-RNP, which presents with varied overlapping symptoms of different connective tissue disorders. The aim of this study is to identify the frequency and patterns of MCTD. Objective :To demonstrate the clinical profile,immunological profile of MCTD patients and adverse events developed during the duration of treatment Design :Prospective observational study Setting : A large, academic, tertiary medical center Methodology:All MCTD cases admitted in Sapthagiri Institute of Medical Sciences and Research Centre was included.Data was collected through a prepared performa.Patients were followed up till death or discharge. Results:All 10 cases of MCTD, U1RNP is positive. 8 of the 10 cases were treated aggressively with immunosuppressants. Most common secondary infection was Pneumonia. One patient developed Abdominal TB One patient developed avascular necrosis of femur secondary to high dose steroids. Interpretation and conclusion:It can be noted that even though the relapse rate was lower among patient treated aggressively the chance of developing secondary infection was very high Hence it is important to monitor the cases which are treated with immunosuppressants, for early diagnosis and treatment of any adverse events. |
| Keywords: | :MCTD,Pneumonia,avascular necrosis |
| Cite Article: | "An observational study to determine clinical profile,immunological profile of MCTD patients and adverse events developed during the duration of treatment.", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 10, page no.b380-b385, October-2023, Available :http://www.ijnrd.org/papers/IJNRD2310141.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2310141 Registration ID: 206825 Published In: Volume 8 Issue 10, October-2023 DOI (Digital Object Identifier): Page No: b380-b385 Country: Chikkabanavara, Karnataka, India Research Area: Medical Science Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2310141 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2310141 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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