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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | ANTI EPILEPTIC BIOACTIVE FACTORS IN A MEDICINAL PLANT CENTELLA ASIATICA |
| Authors Name: | Dr. KANCHI SIVA PRASAD |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_209782
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| Published Paper Id: | IJNRD2311320 |
| Published In: | Volume 8 Issue 11, November-2023 |
| DOI: | |
| Abstract: | Abstract: This study mainly aimed at to investigate the antiepileptic property of a medicinal plant Centella asiatica against the Pentylenetetrazole (PTZ) induced epilepsy. Epilepsy is a convulsive episode and is the most frequent neurodegenerative disorder affecting about 50 million people world-wide. The epileptogenesis is a dynamic process with a tendency to develop hyperexcitability in one or other regions of the central nervous system. Epilepsy is not normally life-threatening, although physical injury can occur as a result of seizures. In rare cases, epilepsy can cause sudden, unexplained death. The primary treatment for epilepsy is the use of antiseizure medicines called anticonvulsant or antiepileptic drugs (AED) to bring seizures under control. Though considerable work has emerged during past several years from other countries, much is awaited from developing countries which are endowed with rich heritage of flora and fauna. It is in this context, efforts have been made in the present study to the neuropharmacological action of Centella asiatica with particular reference to anticonvulsant and neuroprotective activity. Centella asiatica is referred to as one of the great multipurpose miracle herbs of oriental medicine. It is considered as one of the most powerful rejuvenating herbs in Indian Ayurvedic medicine. The active constituents of Centella include triterpenoid glycosides i.e. asiatic acid, asiaticoside, madecassic acid, madecassoside, oxyasiaticoside, and centelloside. Saponin glycosides i.e. brahmiside, brahminoside. Flavonol glycosides i.e. quercetin-3-glycoside and Kampferol-3-glycoside and elements Calcium, Magnesium and Sodium. |
| Keywords: | Key words: Centella asiatica, Epilepsy, Pentylenetetrazole, Triterpenoids. |
| Cite Article: | "ANTI EPILEPTIC BIOACTIVE FACTORS IN A MEDICINAL PLANT CENTELLA ASIATICA", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 11, page no.d218-d228, November-2023, Available :http://www.ijnrd.org/papers/IJNRD2311320.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2311320 Registration ID: 209782 Published In: Volume 8 Issue 11, November-2023 DOI (Digital Object Identifier): Page No: d218-d228 Country: GUDUR/ TIRUPATI DIST., ANDHRA PRADESH, INDIA Research Area: Life Sciences Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2311320 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2311320 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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