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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | FLURBIPROFEN BASED MICROSPONGE: A REVIEW |
| Authors Name: | Mr. Vaibhavkumar Bapu Bhagwat , Mr. Pramod R. More , Mr Uniket M. Gosavi , Mr. Onkar B. Doke |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_210249
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| Published Paper Id: | IJNRD2312037 |
| Published In: | Volume 8 Issue 12, December-2023 |
| DOI: | |
| Abstract: | Flurbiprofen(FP) is a medicine belonging to class of Non Steroidal Anti- Inflammatory Drugs and is classified in class II of BCS having high permeability and low solubility. The end of present study was to formulate the flurbiprofen as a microsponge technology. Microsponges is used to increase the drug release. Flurbiprofen is the class II drug of BCS class having the High Permeability and Low solubility activity. In this Microspongial patented Drug Delivery System, Flurbiprofen drug loaded in cross linked polymers pore. The Quasi emulsion solvent diffusion method introduced for preparation of Flurbiprofen Microsponges. In this method, the internal and external phases employed. Where drug dissolved in mixture of Eudragit RS 100 and dichloromethane as a internal phase and this internal phase add in poly vinyl alcohol as a external phase. Throughout the process ultrasonication, stirring and filtration used to achieve microsponges. The percentage yield, FTIR, entrapment efficiency, dissolution test carried and to increase the entrapment efficiency and percentage yield drug polymer ration used. |
| Keywords: | Microsponges, Flurbiprofen, Low Solubility, Surfactant, External- Internal Organic Phase |
| Cite Article: | "FLURBIPROFEN BASED MICROSPONGE: A REVIEW", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 12, page no.a280-a290, December-2023, Available :http://www.ijnrd.org/papers/IJNRD2312037.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2312037 Registration ID: 210249 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: a280-a290 Country: Dist-Pune, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2312037 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2312037 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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