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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | NEWER APPROACHES OF rDNA TECHNOLOGY IN VACCINE DEVELOPMENT |
| Authors Name: | keerthana g |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_210570
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| Published Paper Id: | IJNRD2312095 |
| Published In: | Volume 8 Issue 12, December-2023 |
| DOI: | |
| Abstract: | An overview of more recent methods for developing vaccines using recombinant DNA (rDNA) technology is given in this article. Through the use of genetic engineering, recombinant vaccines generate antigens or proteins that elicit an immune response. Selecting antigens, copying DNA, transferring genetic material into host cells, and inducing antigen expression are all steps in the process. Benefits of recombinant vaccines include increased protection potential, simplicity of manufacture, safety, and specificity. It explores recombinant DNA technology and explains how processes including DNA separation, alterations using PCR or restriction enzymes, and insertion into a vector may change an organism's genetic composition. This technique is widely used in the pharmaceutical, agricultural, and industrial sectors. It also makes it easier to produce genetically modified crops and therapeutic proteins. A variety of rDNA vaccines are investigated, such as vaccines based on subunits, recombinant proteins, and virus-like particles (VLPs). Subunit vaccines are made of components that have been purified; they have been shown to be safe but may present immunogenicity issues. The hepatitis B and human HPV vaccines are two examples of recombinant protein vaccines that show their effectiveness by expressing certain antigens. Molecularly imitating viruses without infectious characteristics, or VLP vaccines, provide effective and secure immunization alternatives. Finally, we may summarize the advantages of VLP vaccinations, stressing their potential to provide strong immunity, safety, and flexibility in the face of changing virus variations. In general, rDNA technology has revolutionized the development of vaccines by giving scientists the means to create safer and more potent vaccinations against a range of infectious illnesses. The references provide reliable sources that bolster the ideas that have been explored. |
| Keywords: | rDNA Technology, vaccines, genomes, protien vaccines, sub-unit vaccines, recombinant DNA, genetic engineering, VLP vaccines. |
| Cite Article: | "NEWER APPROACHES OF rDNA TECHNOLOGY IN VACCINE DEVELOPMENT", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 12, page no.a777-a781, December-2023, Available :http://www.ijnrd.org/papers/IJNRD2312095.pdf |
| Downloads: | 000118747 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2312095 Registration ID: 210570 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: a777-a781 Country: secunderabad, telangana, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2312095 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2312095 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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