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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | SYNTHESIS, CHARACTERISATION, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF NOVEL BENZOTHIAZOLE DERIVATIVES |
| Authors Name: | Sandhya M , Swaroopa H M , Manoj A Sharon , Nagesh T , Shahabas |
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IJNRD_210312
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| Published Paper Id: | IJNRD2312301 |
| Published In: | Volume 8 Issue 12, December-2023 |
| DOI: | |
| Abstract: | A design and synthesis of new Benzothiazole derivatives(3a-3h) containing thiazole moiety have been synthesized by conventional method by three step process by cyclization to form 2-amino benzothiazole, followed by Schiff’s bases mechanism and electrophilic substitution reaction with benzyl chloride. The synthesized compounds are characterized by 1H-NMR, IR and Mass spectral data. The synthesized compounds are evaluated for invitro antibacterial activity and anthelmintic activity against the antibacterial strains like gram-positive Bacillus substillus, Staphylococcus aureus gram-negative Escherichia coli, Klebsiella pneumoniae species and anthelmintic strains like Earthworms. The Streptomycin is considering as a reference standard drug for Anti- bacterial activity and Albendazole is considering as a reference standard drug for Anthelmintic activity. The compounds 3b, 3e and 3f showed good anti-bacterial activity and the compounds 3a, 3b and 3d showed good anthelmintic activity. |
| Keywords: | Benzothiazole, Antibacterial activity, anthelmintic activity. |
| Cite Article: | "SYNTHESIS, CHARACTERISATION, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF NOVEL BENZOTHIAZOLE DERIVATIVES ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 12, page no.d1-d16, December-2023, Available :http://www.ijnrd.org/papers/IJNRD2312301.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2312301 Registration ID: 210312 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: d1-d16 Country: Mandya, Karnataka , India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2312301 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2312301 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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