INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
A simple, rapid and reproducible HPLC method was developed for determination of Iguratimod in the dosage forms. A SunQ C18 column (250 x 4.6 mm, 5 µ) and a mobile phase of Acetonitrile: Water (80:20 v/v) mixture was used for separation and quantification. Analyses were run at a flow-rate of 1 ml/minwith detection at 256 nm. Under these conditions, Iguratimod eluted at 3.20 min. The developed method was validated according to the ICH guidelines and found to be linear within the range 5– 30 μg/ml. The developed method was applied successfully for quality control assay of Iguratimodin their drug product and dissolution media.The mean % recovery was found to be 99.20 ± 0.98.
Keywords:
High performance liquid chromatography, Iguratimod, Method validation
Cite Article:
"DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR ESTIMATION OF IGURATIMOD IN FORMULATION ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 1, page no.a689-a695, January-2024, Available :http://www.ijnrd.org/papers/IJNRD2401079.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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