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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Evaluation of Anti- Anxiety activity of leaves extract of Adansonia Digitata Linn |
| Authors Name: | Mrs. Dipali Raghuvanshi , Mr. Manoj Jaiswal , Mr. Navdeep Jaiswal , Mr. BN Birla |
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| Author Reg. ID: |
IJNRD_212361
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| Published Paper Id: | IJNRD2401133 |
| Published In: | Volume 9 Issue 1, January-2024 |
| DOI: | |
| Abstract: | Anxiety is a normal emotional behavior, however, becomes pathological precipitating cardiovascular and psychiatric disorders when it is severe. Many allopathic drugs are available to treat anxiety disorders. The Present work summarizes as follows:-in preliminary phytochemical screening Ethanolic extract showed positive results for Flavonoids, Carbohydrates, Saponins compound and Tannins & proteins. Aqueous extract showed presence of carbohydrate, alkaloids, glycosides, steroid, flavonoids and proteins. Ethanolic and Aqueous Adansonia Digitata Linn. Extract was studied for acute oral toxicity as per revised OECD guideline no.- 425 Adansonia Digitata Linn. Was devoid of any toxicity up to 2000 mg/kg in mice by oral route. Hence for further studied doses of 150- 200 mg/ kg of Adansonia Digitata Linn. was used. In Elevated plus Maze Significant increase in time spent in open arm was also observed in each animals treated with standard (Diazepam) drug. The numbers of entries were significant increase in animals treated with ethanol and Aqueous extract and standard drug Diazepam when compared to control animals. In Light Dark Model significant increase in time spent in light area was also observed in each animal treated with standard (Diazepam) drug. The numbers of Transitions were signification increase in animals treated with Ethanol and Aqueous extract and standard drug Diazepam when compared to control animals. the Ethanolic extract of Adansonia Digitata Linn. (200 mg/kg) markedly increased the percentage of average time spent by the animals in the open arms. The anti- anxiety effect of both the doses ( 150 mg/kg ,200 mg/ kg ) showed significant activity at being that 2000 mg/ kg show higher activity. The anti-anxiety activity effects of Ethanolic and Aqueous extract of Adansonia Digitata Linn. may be attribute to any of our combination of chemicals present in the extract. |
| Keywords: | Adansonia Digitata Linn, anti- anxiety effect. |
| Cite Article: | "Evaluation of Anti- Anxiety activity of leaves extract of Adansonia Digitata Linn", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 1, page no.b286-b294, January-2024, Available :http://www.ijnrd.org/papers/IJNRD2401133.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2401133 Registration ID: 212361 Published In: Volume 9 Issue 1, January-2024 DOI (Digital Object Identifier): Page No: b286-b294 Country: Dhamnod, MP, India Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2401133 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2401133 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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