INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
The global spread of drug resistance in bacteria requires new potent and safe antimicrobial agents. The Triazole derivatives possess divers biological activities such as antibacterial, antifungal, antiviral, anti-tubercular, anti-inflammatory, analgesic, antitumor, anticonvulsant and some other biological as well as chemical useful compounds. The biological profile of triazole moiety has attracted the attention of many researchers to explore its multiple potential against several biological activities. Compounds containing the 1, 2, 3-Triazole and 1, 2, 4-Triazole derivatives have acquired conspicuous significance due to their wide spectrum of biological activities. Triazole and its derivatives possess a great importance in medicinal chemistry and can be used for the synthesis of various compounds with different types of biological activities. A large volume of research on triazole and their derivatives has been carried out, proving significant antibacterial activity of this heterocyclic core. There is a growing demand for the preparation of new antimicrobial agents due to the developing resistance towards conventional antibiotics. The 1,2,3- triazole moiety does not occur in nature, although the synthetic molecules that contain 1,2,3-triazole units show diverse biological activities. This article covers the information of some triazoles derivatives having antimicrobial activities. Thus, triazole acts as a promising medicinal agent and can be helpful to develop new triazole compounds that could have better efficacy and lesser toxicity.
Keywords:
1,2,4-Triazole. Biological activity. Schiff Base.
Cite Article:
"SUBSTITUTED-TRIAZOLES AND THEIR SCHIFF BASES AS ANTI-MICROBIAL AGENTS: A GENERAL REVIEW ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 1, page no.b441-b450, January-2024, Available :http://www.ijnrd.org/papers/IJNRD2401148.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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