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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | PATHOPHYSIOLOGY OF DIFFERENT CARDIOVASCULAR COMPLICATIONS IN CHRONIC KIDNEY DISEASE PATIENTS. |
| Authors Name: | Lipika Julka , DR. Nitesh Motla , DR. Deepa Muthiah |
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IJNRD_216729
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| Published Paper Id: | IJNRD2404387 |
| Published In: | Volume 9 Issue 4, April-2024 |
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| Abstract: | Abstract : Chronic Kidney Disease (CKD) is a global health concern with a rising prevalence, and its impact extends beyond renal dysfunction to encompass a spectrum of systemic complications. Among these, cardiovascular complications represent a significant cause of morbidity and mortality in CKD patients. This abstract provides a comprehensive overview of the intricate relationship between CKD and cardiovascular disorders.The pathophysiological mechanisms linking CKD and cardiovascular complications are multifaceted and include traditional risk factors such as hypertension, dyslipidemia, and diabetes, as well as non-traditional factors like inflammation, oxidative stress, and mineral metabolism disturbances. The uremic milieu contributes to endothelial dysfunction, vascular calcification, and a prothrombotic state, all of which contribute to the heightened cardiovascular risk in CKD. Epidemiological studies have consistently demonstrated a strong association between declining renal function and increased cardiovascular events. This review explores the clinical manifestations of cardiovascular complications in CKD patients, including ischemic heart disease, heart failure, arrhythmias, and sudden cardiac death. Moreover, it discusses the challenges in risk stratification and management strategies unique to this population.Recent advancements in research have shed light on novel biomarkers and imaging modalities that may enhance our understanding of cardiovascular risk in CKD. Additionally, emerging therapeutic interventions, ranging from pharmacological agents targeting specific pathways to lifestyle modifications and renal replacement therapies, are discussed in the context of preventing and managing cardiovascular complications in CKD. METHODS: A comprehensive review of the existing literature was conducted to evaluate the cardiovascular complications associated with CKD patients. Relevant studies, case reports, and official reports were analyzed to identify the types, mechanisms, and incidence of these complications. |
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| Cite Article: | "PATHOPHYSIOLOGY OF DIFFERENT CARDIOVASCULAR COMPLICATIONS IN CHRONIC KIDNEY DISEASE PATIENTS.", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 4, page no.d787-d796, April-2024, Available :http://www.ijnrd.org/papers/IJNRD2404387.pdf |
| Downloads: | 00039 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2404387 Registration ID: 216729 Published In: Volume 9 Issue 4, April-2024 DOI (Digital Object Identifier): Page No: d787-d796 Country: NEW DELHI, DELHI, India Research Area: Health Science Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2404387 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2404387 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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